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Axion BioSystems metric plotting tool 2.5.0
Metric Plotting Tool 2.5.0, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/metric+plotting+tool+2%2E5%2E0/neuralmetric+tool+2+0+4/pm40272900-115-11-15
Average 90 stars, based on 1 article reviews
metric plotting tool 2.5.0 - by Bioz Stars, 2026-09
90/100 stars

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Article Title: In vitro seizure risk assessment using a microelectrode array and comparison with an in vivo rat study.
Article Snippet: Drug-induced convulsions/seizures are a serious adverse event in the clinic; however, precise convulsion/seizure risk assessment remains challenging, particularly in the early phase of drug development.. There is a demand for reliable in vitro assay systems that can predict in vivo convulsions.. Here, we investigated the usefulness of in vitro microelectrode array (MEA) assays using rat primary neurons by comparing them with an in vivo convulsion study for 14 reference drugs known to cause seizure/convulsion: Paroxetine, 4-aminopyridine, pentylenetetrazol, strychnine, amoxapine, fluvoxamine, linopirdine, theophylline, pilocarpine, tramadol, bupropion, diphenhydramine, kainic acid, and veratridine.



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